Weight Management & Metabolic Support
Retatrutide works across three key hormonal pathways involved in appetite signaling, energy expenditure and metabolic regulation. This multi-receptor approach is designed to support meaningful weight-management outcomes while aligning with nutrition, movement and recovery strategies.
- Supports appetite signaling pathways
- Supports metabolic rate and energy utilization
- Designed for individuals needing advanced metabolic support

Appetite Regulation & Satiety Support
By acting on GLP-1 and GIP receptors, retatrutide is designed to help support feelings of fullness and reduce persistent hunger cues. This can make it easier to maintain consistent nutrition patterns and protein-forward meal planning.
- Supports satiety signaling
- Helps reduce frequent snacking urges
- Supports adherence to structured nutrition plans
Energy Balance & Fat-Utilization Support
The addition of glucagon receptor activity is intended to support energy balance and fat-utilization pathways. This differentiates retatrutide from single- or dual-agonist therapies and contributes to its investigational profile.
- Supports fat-utilization mechanisms
- Supports metabolic flexibility
- Complements movement and resistance training routines
Glucose & Metabolic Rhythm Support
Retatrutide is designed to support normal glucose handling and overall metabolic rhythm, which can help individuals feel more consistent throughout the day when paired with balanced meals, hydration and movement.
- Supports glucose regulation pathways
- Complements lifestyle-based metabolic strategies
- Designed to support long-term consistency



